Come vacation in the Lake Region of Florida. This is the area around Keystone Heights - Melrose. In this region we have the beautiful Lake Santa Fe, a 6000 acre cypress lined paradise. Many visitors say Santa Fe looks like “old Florida.” With the moss covered oak trees and beautiful sunsets it is relaxing and brings on thoughts of simpler times. Santa Fe is great for swimming, fishing, and boating or just relaxing. The region also offers other lakes that are clear water and sandy bottoms that are perfect for any type of water sport.

Melrose is just a short drive from Gainesville (15 Min), less than an hour from Jacksonville, and about two hours from Orlando.

Century 21 Lakeside Realty will help you find a vacation rental to suite your desires, from the elegant to the fisherman's cabin.

Contact Information

Vacation rentals are managed by Dean Smith.

311 State Road 265 Melrose, Fl. 32666

Office #: 352-475-1121

Cell#: 352-214-8077

Toll Free: 877-213-7129

Rental Rates

Weekly - $550-$1600

Daily - $100-$250